RESEARCH / 01
Cellular clues to endogenous repair
Animal model · Repair mechanisms
Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy
In a mouse model of partial nephrectomy, Notch signaling was involved in activating Sox9-positive cells, and renal tubular repair was observed.
What this study examined
- Mouse model of unilateral partial nephrectomy
- Sox9+ cells appeared on postoperative day 1 and persisted through day 20
Why the study matters
Activating endogenous repair: tracing the activation and differentiation of Sox9-positive cells after kidney injury.
Open original paper Back to the full evidence libraryBIO-PILOT ESSENCE / 003
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